It happens all the time in my books, at least.
I write the kind of mysteries where the main characters sort of fall into trouble. A pig digs up a body under a rose bush (Candy); an angry lover from the past comes back to threaten someone (Nowhere to Run); a woman finds a body in a greenhouse (Lilacs).
Well, you get the idea. I'm one of those writers who can see a plot possibility anywhere. And since I'm not an international traveler or a spy or a cop, the "anywhere" I see is all around me, at writer's conferences (Autographs), at restaurants (Foxgloves), or in a small town in Iowa (Brilliant Disguise).
So I think it's easy to fall into danger -- no matter where you are!
(dangerous books ahead!)